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Rob Bettigole

Robert A. Bettigole

Lecturer in the Practice of Management

Rob Bettigole is the founder and a managing partner of Elm Street Ventures. His previous roles at SOM include Entrepreneur-in-Residence (2004-2014), and Executive Fellow (2014-2017). At Elm Street Ventures, Rob serves on the boards of P2 Science (where he is Chairman) and Allyx Therapeutics, both Yale spinouts. Previously, Rob was a board member of AxioMx, Occam Sciences, SeeClickFix, ShareGrove, and Retail Optimization Inc., and served as an observer on the boards of Affomix, Arvinas, BioRelix, Device42, Halda Therapeutics, and Metagenomix.

Before founding ESV in 2006, Rob ran an infrastructure business and helped found several start-ups. Earlier in his career, he was a venture capitalist with Rothschild Inc. and Investor AB. He began his professional career as an electrical engineer, mainly working in software and signal processing. Rob served on the Operating Board of the Yale Entrepreneurial Institute from its inception in 2007 and is on the Investment Committee of the College Street Innovation Fund, which Elm Street Ventures also manages.

He is an Entrepreneur-in-Residence at Yale’s Office of Cooperative Research. Rob is on the boards of BioCT and the New Haven innovation Collaborative. He is a Licensed Professional Engineer and holds several U.S. and foreign patents.


  • MPPM, Yale School of Management, 1983
  • BS, Yale University, 1976